Bone Morphogenetic Proteins, A Realistic Alternative to Bone Grafting<br>
LOD-054-00
Dr. Ulf Wikesjo
Surgical placement of oral implants is governed by the prosthetic design and by the morphology and quality of the alveolar bone. Often, implant placement may be difficult, if at all possible, due to alveolar ridge aberrations. In consequence, prostheticly dictated implant positioning commonly entails bone augmentation procedures. One objective of our laboratory is to evaluate the biologic and clinical potential of bone morphogenetic proteins (BMPs) including rhBMP-2, rhOP-1/rhBMP-7, rhGDF-5, other candidate biologics, bone biomaterials, and devices for alveolar ridge augmentation and implant fixation. This presentation will discuss the unique biologic potential, the clinical relevance and perspectives of BMP technologies for alveolar bone augmentation and oral implant fixation, in particular the development of a unique bone-inductive oral implant. This presentation will also address merits and explain short-comings of current treatment protocol including bone biomaterials and guided bone regeneration (GBR). BMPs have an unparalleled potential to augment alveolar bone and support implant osseointegration and long-term functional loading. Inclusion of BMPs for alveolar augmentation and osseointegration will not only enhance predictability of existing clinical protocol but radically change current treatment paradigms. Inclusion of the bone-inductive oral implant in the treatment panorama may make 'grafting' and GBR procedures altogether obsolete.
Soft Tissue Behaviour And Integration Around Dental Implants <br>
LOD-021-00
Dr. Peter Schupbach
The scientific evidence on the biomaterial surface TiUniteTM will be given and compared to other implant surfaces. Several studies confirm and support the clinical benefits of the conductive properties of TiUniteTM, allowing bone and soft tissue to adhere along the implant surface and into the pores of the surface. This results in faster osseointegration and higher biological stability, thus minimizing time at risk for effective and safe Immediate FunctionTM. The clinical implications of TiUnite as Immdiate FunctionTM, reduced marginal bone loss, soft tissue integration and predictable esthetics will be discussed. In addition the scientific evidence of micro grooves along the threads and around the implant shoulder will be given. The introduction of the Groovy technology provides yet another step in implant development. With this technology, the speed of osseointegration can be further increased. The biological stability is enhanced by up to 30% allowing the use of groovy implants in soft bone.
Biological Data for Bone Integration
LOD-018-00
Dr. Peter Schupbach
The scientific evidence on the biomaterial surface TiUniteTM will be given and compared to other implant surfaces. Several studies confirm and support the clinical benefits of the remarkable osseoconductive properties of TiUniteTM, allowing bone to grow along the implant surface and into the pores of the surface. This results in faster osseointegration and higher biological stability, thus minimizing time at risk for effective and safe Immediate FunctionTM. The clinical implications of TiUnite as Immdiate FunctionTM, reduced marginal bone loss, soft tissue integration and predictable esthetics will be discussed. In addition the scientific evidence of micro grooves along the threads and around the implant shoulder will be given. The introduction of the Groovy technology provides yet another step in implant development. With this technology, the speed of osseointegration can be further increased. The biological stability is enhanced by up to 30% allowing the use of groovy implants in soft bone.